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Description

HemorheologlcAgent a drug that improves the flow properties of blood by reducing viscosity (pentoxifylline) prostate oncology specialists los angeles buy casodex 50mg fast delivery. Hemostatic, Local a drug applied to a bleeding surface to promote clotting or to serve as a clot matrix (thrombin, clot promoter; oxidized cellulose, clot matrix). Hemostatic, Systemic a drug that stops bleeding by inhibiting systemic fibrinolysis (aminocaproic acid). Histamine H 1 Receptor Antagonist a drug used to combat the histamine-induced symptoms of allergy; an antihistamine (diphenhydramine hydrochloride). Histamine H2 Receptor Antagonist a drug that inhibits histamine-mediated gastric acid secretion; it is used to treat peptic and duodenal ulcers (famotidine). Hormone a drug that duplicates the action of a physiological cell regulator (hormone) (insulin, estradiol, thyroxine). Hydantoin an antiepileptic drug that contains the hydantoin moiety in its chemical structure (phenytoin sodium). K Keratolytic a topical drug that toughens and protects skin (compound benzoin tincture, salicylic acid). L Luative a drug that promotes defecation, usually considered milder in action than a cathartic (psyllium mucilloid, bulk laxative; mineral oil, lubricant laxative; sodium phosphates oral solution, saline laxative; bisacodyl, irritant laxative). Leukotriene Receptor Antagonist a drug that inhibits leukotrienes or fatty compounds produced by the immune system that cause inflanunation in asthma and bronchitis and constrict airways (montelukast). Lipase Inhibitor a drug used to reduce the activity of lipases found in the intestine secreted by the pancreas when fat is present (orlistat). Ovulation Stimulator a drug that is similar to estrogen and binds to the estrogen receptor causing a negative feedback that stimulates the release of gonadotropin releasing hormone that activates the pituitary gland to release follicle-stimulating hormone and luteinizing hormone with resultant release of an egg clomifene). Oxytocic a drug that stimulates uterine motility; it is used in obstetrics to initiate labor or to control postpartum hemorrhage oxytocin). Metal Complexing Agent a drug that binds metal ions; it is useful in treating metal poisoning (dimercaprol, complexing agent for arsenic, mercury, and gold). Mineralocorticoid an adrenocortical hormone that regulates sodium/potassium balance in the body (desoxycorticosterone acetate). Miotic a cholinergic drug used topically in the eye to induce constriction of the pupil (miosis) (pilocarpine). Monoamine Oxidase Inhibitor an antidepressant drug that inhibits the enzyme monoamine oxidase, thereby increasing catecholamine levels of neurons (isocarboxazid). Mucolytic a drug that hydrolyzes mucoproteins; it is useful in reducing the viscosity of pulmonary mucus (acetylcysteine). Muscle Relaxant, Smooth a drug that inhibits the contraction of visceral smooth muscles (aminophylline). Mydriatic an adrenergic drug used topically in the eye to induce dilation of the pupil (mydriasis) (phenylephrine). Pediculicide an insecticide suitable for eradicating louse infestations (pediculosis) (malathion; permethrin).

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The duodenum: a is almost completely covered by peritoneum b lies behind the portal vein c lies anterior to the hilum of the right kidney d is crossed anteriorly by the superior mesenteric vessels e is about 25 cm long T/F ( ) ( ) ( ) ( ) ( ) Answers 1 androgen hormone overload casodex 50mg with visa. The remainder lies retroperitoneally, with only its anterior surface and sides being covered. The appendices epiploicae are small numerous fat-laden peritoneal tags seen over most of the large bowel; the taeniae coli are flattened bands of longitudinal muscle that create the characteristic haustrations of the large bowel. The ileum can be distinguished from the jejunum because the ileum has: a thicker walls than the jejunum b fewer valvulae conniventes than the jejunum c appendices epiploicae and, occasionally, taeniae coli d less fat in its mesentery e fewer arterial arcades T/F ( ) ( ) ( ) ( ) ( ) 3. The structures on which the stomach lies are often referred to as the stomach bed. This results in distension of the appendix and stimulates visceral pain afferents, which are carried by sympathetic nerves to the T10 spinal cord level. Later, when the continuing obstruction causes local inflammation in the appendicular wall, the parietal peritoneum in the region becomes inflamed to produce tenderness and pain in the right iliac fossa. Splenic flexure of the colon Match the following statements with the appropriate item(s) from the above list. The foregut extends as far as the point of entry of the ampulla of Vater into the second part of the duodenum and comprises the lower oesophagus, the stomach and the proximal duodenum, together with the liver, spleen and pancreas. Barium radiographs, small bowel enemas or barium meals and follow-throughs reveal that the small bowel is seen in the central abdomen with indentations of the circular folds of the mucosa, which commence in the second part of the duodenum but disappear by the mid-ileum. A barium enema reveals sacculations or haustrations, especially in the transverse colon, and particularly if the radiographic examination is by the double-contrast technique, in which a mixture of gas and the contrast medium is used to emphasize the fine mucosal pattern. The pattern is caused by the relative shortness of the longitudinal muscle (taeniae coli) of the colon compared with that of the circular muscle it encloses. The sacculations are rather like the appearance of a piece of woven material in which a thread has been pulled. Bailey & Love · Essential Clinical Anatomy · Bailey & Love · Essential Clinical Anatomy Essential Clinical Anatomy · Bailey & Love · Essential Clinical Anatomy · Bailey & Love Clinical Bailey & Love · Essential Clinical Anatomy · Bailey & Love · EssentialChapterAnatomy 7 the liver, spleen and pancreas · · · · · the liver. It possesses two surfaces, a rounded diaphragmatic and an irregular visceral (inferior) surface. The diaphragmatic surface is rounded and convex, fitting closely to the diaphragm. It is divided into a right and a smaller left lobe by the interlobar fissure, the ligamentum venosum superiorly and the ligamentum teres below. The ligamentum venosum is a remnant of the ductus venosus which, in the fetus, connects the umbilical vein and inferior vena cava and allows blood to bypass the liver.

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Specifications/Details

H the product is packaged under aseptic conditions prostate cancer books buy generic casodex 50mg on-line, sterility may also be maintained during the shelf life of the product. Topical medication may be applied in a uniform thin layer to the skin without anything else touching the affected area. This method of application may reduce the irritation that sometimes ae<:ompanies mechanical (fingertip) application of topical preparations. The numeric designations are arrived at by the following method: (a) the digit at the extreme right refers to the number of fluorine atoms in the molecule. The number of chlorine atoms in a molecule may be determined by subtracting the total number of hydrogen and fluorine atoms from the total number of atoms, which may be added to the carbon chain. Aerosol application is a clean process, requiring little or no washup by the user. The Aerosol Principle An aerosol formulation consists of two component parts: the product concentrate and the propellant. The product concentrate is the active ingredient of the aerosol combined with the required adjuncts, such as antioxidants, surface-active agents, and solvents, to prepare a stable and efficacious product. When the propellant is a liquefied gas or a mixture of liquefied gases, it frequently serves the dual role of propellant and solvent or vehicle for the product concentrate. In certain aerosol systems, compressed gases-carbon dioxide, nitrogen, and nitrous oxide-are employed as the propellant. However, these propellants are being phased out and will be prohibited for nonessential use under federal regulations following recognition that they reduce the amount of ozone in the stratosphere, which results in an increase in the amount of ultraviolet radiation reaching the earth, an increase in the incidence of skin cancer, and other adverse environmental effects. A number of metered-dose pharmaceutical products for oral inhalation have received such essential use exemptions. Fluorinated hydrocarbons are gases at room temperature They may be liquefied by cooling below their boiling point or by compression at room temperature. For example, dichlorodifluoromethane (Freon 12) will form a liquid when cooled to -30"C (-22"F) or when compressed to 70 psig (pounds per square inch gauge) at 21°C (70°F). Both of these methods for liquefying gases are employed in aerosol packaging, as discussed later in this section. The vapor phase exerts pressure in all directions-against the walls of the container, the valve assembly, and the surface of the liquid phase, which is composed of the liquefied gas and the product concentrate. It is this pressure that, upon actuation of the aerosol valve, forces the liquid phase up the dip tube and out of the orifice of the valve into the atmosphere. As the propellant meets the air, it expands and evaporates because of the drop in pressure, leaving the product concentrate as airborne liquid droplets or dry particles, depending upon the formulation.

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Because of the different rates and degrees of absorption obtainable from drugs of various particle sizes prostate cancer zonal anatomy order casodex 50mg visa, products of the same drug substance prepared by two or more reliable pharmaceutical manufacturers may result in different degrees of therapeutic response in the same individual. A classic example of this occurs with phenytoin sodiwn capsules, which have two distinct forms. The former has a dissolution rate of not less than 85% in 30 minutes and is recommended for use three to four times per day. The latter has a slower dissolution rate, for example, 15% to 35% in 30 minutes, which lends itself to use in patients who can be dosed less frequently. Because of such differences in formulation for a number of drugs and drug products, it is generally advisable for a person to continue taking the same brand of medication, provided it produces the desired therapeutic effect. Patients who are stabilized on one brand of drug should not be switched to another unless necessary. However, when a change is necessary, appropriate blood or plasma concentrations of the drug should be monitored until the patient is stabilized on the new product. Occasionally, a rapid rate of drug absorption is not desired in a pharmaceutical preparation. Research pharmacists who wish to provide sustained rather than rapid action may employ agents of varying particle size to provide controlled dissolution and absorption. Summaries of the physicochemical principles of particle size reduction and the relation of particle size to surface area, dissolution, and solubility may be found in Physical Pharmacy Capsule 4. Crystal or Amorphous Drug Form Solid drug materials may occur as pure crystalline substances of definite identifiable shape or as amorphous particles without definite structure. The amorphous or crystalline character of a drug substance may be of considerable importance to its ease of formulation and handling, its chemical stability, and as has been recently demonstrated, even its biologic activity. Certain medicinal agents may be produced to exist in either a crystalline or an amorphous state. Because the amorphous form of a chemical is usually more soluble than is the crystalline form, different extents of drug absorption may result with consequent differences in the degree of pharmacologic activity obtained from each. Two antibiotic substances, novobiocin and chloramphenicol palmitate, are essentially inactive when administered in crystalline form, but when they are administered in the amorphous form, absorption from the gastrointestinal tract proceeds rapidly, with good therapeutic response. In other instances, crystalline forms of drugs may be used because of greater stability than the corresponding amorphous forms. For example, the crystalline forms of penicillin G as the potassium salt or sodium salt are considerably more stable than are the analogous amorphous forms. Thus, in formulation work on penicillin G, the crystalline forms are preferred and result in excellent therapeutic response. The hormone insulin presents another striking example of the different degree of activity that may result from the use of different physical forms of the same medicinal agent.

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Customer Reviews

Uruk, 56 years: These fixed combinations were developed to give better control for diabetes patients who use a combination of short- and long-acting insulins. Maximum clarity, fullest hydration, and highest viscosity will be obtained if the gel is cooled to ooc to l0°C (32°F to 50°F) for about an hour.

Redge, 40 years: In each space infected peritoneal fluid can accumulate to form subphrenic abscesses. These tension-lowering substances are surface active (surfactants) or wetting agents or some select categories of emulsifying agents.

Masil, 53 years: Nasal Route for Systemic Effects the nasal route for drug delivery is of interest because of the need to develop a route that is neither oral nor parenteral for newly developed synthetic, biologically active peptides and polypeptides (12-17). To facilitate acceptance, the pharmacist should point out that the bottle or container of medication should first be warmed in the hands and, if the product is a suspension, shaken prior to withdrawal into the dropper.

Bozep, 41 years: The lower plate is removed and the capsules allowed to fall out of the plate onto a surface for examination. Each individual monograph for the official injection states the type of container (single dose and/or multiple dose) pennitted for the injection, the type of glass preferred for the container.

Dudley, 25 years: It is prepared by dissolving 85 g of sucrose in enough purified water to make 100 mL of syrup. Amyl nitrite, for example, is a clear yellowish liquid that is volatile even at low temperatures and is also highly flammable.

Giacomo, 54 years: Pharmacokinetic differences between women and men may be particularly important for drugs having a narrow therapeutic index, in which the smaller average size of women may necessitate modified dosing. When water alone is employed as the menstruum, alcohol is frequently added to the extractive or to the final preparation as an antimicrobial preservative.

Lee, 58 years: Different rates of drug release may be obtained by changing the ratio of core to wall, the polymer used for the coating, and the method of microencapsulation (15). It is conceivable that when it is used as an adjunct to cancer chemotherapy, prescriptions for this product will be written for 7 to 10 vials.

Potros, 39 years: Sorption may occur with active pharmacologic agents or with pharmaceutical excipient&. According to federal regulations, drug labeling includes not only the labels placed on an immediate container but also the information on the packaging, in package inserts, and in company literature, advertising, and promotional materials.